David Stein

David Stein

Research Scientist

Flatiron Institute


I’m a Research Scientist in the Biophysical Modeling Group, part of the Center for Computational Biology at the Flatiron Institute. My research focuses on understanding fluid-structure interactions in complex and active fluids. Understanding the features of such systems requires utilizing a wide range of tools, most of which either do not yet exist or which don’t exist in the required form. Over the past several years, I’ve spent time developing new numerical methods that allow rapid simulations of a wide range of complex or active fluids in nontrivial evolving geometries, deriving continuum models for dense carpets of elastic filaments immersed in fluids, and using these new tools to generate insight into the behavior of the basic mathematical equations used and the biological systems that these equations model.


Flow driven sculpting of dissolving solids

Semi-lagrangian and boundary integral schemes for complex and active fluids

Rotor Proteins in Membranes

Coarse grained fiber beds

Systems of dense fibers play a pivotal role in a wide range of biological phenomenon, from mucosal clearance by ciliary pumping to the centering of the mitotic spinidle. In this project, we construct a Brinkman-like coarse grained model for beds of cilia based on local slender body theory.

High-order Immersed Boundary Methods